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DNA Extraction Instruments

DNA Extraction Instruments

Accelerating Genomics: How Automated DNA Extraction Is Powering High-Throughput Research

The Future of DNA Extraction Is Automated—and Affordable

In today’s fast-paced genomic landscape, automated DNA extraction is rapidly replacing traditional manual protocols. As laboratories scale up operations to meet growing demands for agricultural biotechnology and genomics research, automation is no longer a luxury—it’s a necessity.

Meet GeneExtract: High-Throughput DNA Extraction That Delivers Speed, Purity, and Unbeatable Value

At 3CR Bioscience, we’ve developed two powerful, cost-effective DNA extraction instruments to meet this need: the GeneExtract H9600 and the GeneExtract H384. Designed to deliver high-purity nucleic acid extractions with unmatched speed, efficiency, and affordability, these platforms are built for labs working with high-throughput leaf, seed, blood and tissue DNA extraction for research and development purposes. Whether you’re comparing against industry leaders, or moving away from labour-intensive manual workflows, 3CR Bio’s solutions stand out on performance—and price.

Image showing full, walk-away automation with DNA extraction instruments and a robotic arm for ultra high-throughput purification of high numbers of DNA samples per day.

Why Automated DNA Extraction?

The Challenges of Manual Extraction

Manual DNA extraction, while traditionally used, is increasingly impractical for labs processing hundreds—or thousands—of samples per week. It’s laborious, time-consuming, and prone to variability, introducing the risk of contamination and inconsistent results. Automated DNA extraction eliminates these bottlenecks by standardising processes, improving reproducibility, and dramatically increasing throughput.

The Benefits of Automation

With instruments like the GeneExtract H9600 and H384, extraction becomes faster, cleaner, and more scalable. And crucially, the cost per sample is often significantly lower than with manual extraction—particularly when you factor in labour, consumables, and sample loss due to human error.

Interior of the GeneExtract H384 DNA extraction instrument showing the layout of sample plates and deep-well buffer plates for the purification of high-quality DNA from four 96-well sample plates in 30 minutes.

Introducing the GeneExtract H9600 and H384: Smart Automation, Scaled to Your Workflow

3CR Bioscience’s GeneExtract series offers two platforms tailored to the needs of high-throughput laboratories:

GeneExtract H9600

  • Capacity: 1 x 96-well plate (up to 96 samples per run)
  • Runtime: 25–30 minutes per cycle
  • Best for: Labs needing consistent throughput with single-plate processing

GeneExtract H384

  • Capacity: 4 x 96-well plates (up to 384 samples per run)
  • Runtime: 25–30 minutes per cycle
  • Best for: Large-scale facilities needing high-throughput DNA extraction across varied sample types

Both systems support magnetic bead-based nucleic acid purification, providing high-quality DNA ideal for applications such as PCR, sequencing, PACE® SNP genotyping, and microarrays. They feature pre-loaded protocols, an intuitive touchscreen interface, and built-in contamination control via UV sterilisation and HEPA-filtered airflow.

Application Spotlight: Plant Genotyping & Seed Testing

The GeneExtract systems are widely used in agricultural biotechnology, where leaf and seed DNA extraction is essential for crop improvement, trait analysis, and quality control. Here’s how they fit into real-world workflows:

  • Breeding Programs: Rapid, reliable DNA extraction enables fast genotyping of hundreds of seed or leaf samples to select for desirable traits.
  • Seed Purity Testing: Automated extraction provides consistent nucleic acid yields necessary for accurate hybrid purity assessment.
  • NGS Workflows: High-integrity DNA from GeneExtract systems supports downstream library prep and sequencing, ensuring efficient, reliable data generation.

Thanks to the modular flexibility of the H384, labs can scale up or down depending on project size, processing 1–4 plates per run without compromising on speed or quality.

Manual vs Automated DNA Extraction: A Direct Comparison

FeatureManual ExtractionAutomated DNA Extraction (H9600/H384)
Hands-On TimeHigh (45–90 min)Low (setup only; 25–30 min runtime)
ThroughputLimited (1–24 samples)High (up to 384 samples/run)
Contamination RiskModerate–HighLow (UV/HEPA systems)
ReproducibilityVariable (operator dependent)High (standardised protocols)
Sample Loss/ErrorCommonRare (automated handling)
Labour CostHighLow (minimal supervision needed)
Per Sample CostVariable; often higherLower (especially with 3CR’s low-cost consumables)

Transitioning to automated DNA extraction can reduce turnaround time by over 70% while boosting accuracy and consistency across batches—benefits that are essential for high-throughput labs.

Designed for Lab Flexibility

Both the H9600 and H384 are plug-and-play, requiring no air or water hookups and minimal setup. The stackable design of the H384 allows up to three units to be combined, offering processing capacity of over 1,000 samples per hour within a compact footprint.

Customisable protocols, compatibility with a wide range of magnetic bead-based extraction kits, and built-in sample protection (over-temperature alarms, power failure recovery) make the GeneExtract range ideal for a variety of genomics and diagnostic workflows.

Exceptional Value Without Compromise

One of the biggest barriers to automation is often the cost—but that’s exactly where 3CR Bioscience offers a clear advantage.

Our systems are engineered to keep consumable costs low. Unlike competitors that lock you into proprietary plastics or expensive service contracts, our H9600 and H384 use only tip combs and deep-well plates, which are available at a fraction of the cost from 3CR.

“With GeneExtract, we’re not just automating DNA extraction—we’re making it accessible. Our goal is to empower every lab to work faster, cleaner, and smarter, without breaking the budget.” – 3CR Bioscience Product Team

This makes our systems ideal for academic institutions, agritech startups, and biotech companies scaling up operations without enterprise-sized budgets.

Built-In Support & Consumables Designed for Performance

To ensure maximum uptime and performance, 3CR offers dedicated service and support, including:

  • Spares & Support Kits with essential parts and remote engineer access
  • On-site support from experienced field engineers
  • High-quality consumables like:

These consumables ensure maximum recovery, protect the lifespan of your magnetic rods, and support contamination-free workflows.

Real-World Results, Backed by Science

Across customer labs, the GeneExtract series is already helping accelerate genomics projects with precision and speed:

  • Biotech Firms use the H9600 for rapid DNA prep from leaf tissue in crop research.
  • Agricultural Research Centres rely on the H384 for bulk DNA extractions from seed banks.
  • Academic Core Facilities choose 3CR Bio to reduce cost-per-sample and improve throughput without expanding headcount.

In all cases, users report better reproducibility, staff freed for more applied research, and significant time savings over manual methods.

Conclusion: The Future of DNA Extraction Is Automated—and Affordable

As the need for high-throughput DNA analysis grows, automated DNA extraction is becoming the standard. With the launch of the GeneExtract H9600 and H384, 3CR Bioscience is helping labs stay ahead of the curve—delivering performance on par with top-tier systems but at a much more accessible price point.

Whether you’re scaling up plant genotyping, streamlining NGS workflows, or replacing manual extraction protocols, the GeneExtract platform offers the reliability, speed, and cost-efficiency your lab needs to thrive.

Ready to upgrade your DNA extraction workflow?

Explore the GeneExtract H9600 and H384 today—and see how affordable automation can be.

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MEET OUR TEAM

Steve Asquith Managing Director
Steve began his career in the Genetics Division of GlaxoSmithKline, as part of the team establishing GSK’s high-throughput core genotyping laboratory. Steve joined KBioscience when it was first founded in 2002 and was a key driver in taking the company from a small start-up to a multi-national service laboratory, quickly growing the company’s revenue to over $7.5M p.a. Following the acquisition of Kbioscience by LGC in 2011, Steve was appointed Global Director of Operations for LGC Genomics, responsible for over 100 staff in Europe and N. America, successfully elevating the genotyping products and service business. Steve held a crucial leadership role until he left in 2016. In 2017 Steve joined forces with John Holme to create 3CR Bioscience, a new company with a mission to deliver outstanding, customer-focused genotyping products with innovation and affordability at its core.
Dr. John Holme Technical Director
John joined KBioscience shortly after it was founded, in 2003, and became Head of Technical Development, building the company’s genotyping and DNA extraction product portfolio and service delivery until 2011 when it was acquired by LGC. Post-acquisition, John was appointed Head of Technical Group for LGC Genomics, in charge of all Research & Development and Technical Support activities for the company. In this role John continued to build on the high-quality products and services provided to the companies growing customer base. During the 19 years John has worked in commercial R&D, he has co-invented numerous highly successful products including PACE®, ProbeSure, KASP™, KlearKall, KlearGene, KlearAmp and KlearTaq™, creating breakthrough offerings in genotyping and extraction and generating huge revenues for the companies he has worked in. In 2017, he joined forces with Steve Asquith and started 3CR Bioscience. John is dedicated to developing outstanding, innovative genotyping products and providing the very best technical support to customers globally.
Dr. Nisha JainOperations Director
Nisha has been innovating since the start of her career at Geneform Technologies developing Iso-thermal Genotyping Technologies. Nisha joined KBioscience in 2008, as Senior R&D Scientist and key account Technical Support Scientist, developing KASP and Klearkall performance and coinventing two further versions of KASP. Nisha has more than 15 years’ experience working in molecular biology and genotyping technologies, with extensive experience in the areas of R&D, Quality Assurance and Customer Technical Support. She has technically assisted many giants of the industry with their protocol development and troubleshooting and continues to deliver high-quality support and guidance. In 2018, Nisha joined 3CR Bioscience as Operations Director where she continues to develop PACE and ProbeSure for an increasing range of applications, and to grow 3CR Bioscience’s new product pipeline. Nisha is dedicated to developing outstanding, innovative genotyping products and providing the very best technical support to customers globally.
Nazma Saffin General Manager
For 20 years Nazma Saffin has worked and gained extensive expertise within the genotyping sector. Working at Kbioscience and then LGC, she has held operational leadership posts responsible for manufacturing and laboratory services. With experience of ISO 9001 implementation, production scale up and LEAN operations, Nazma has successfully led highly profitable production departments. Joining 3CR Bioscience in 2022, Nazma is committed to delivering operational excellence.
Jon Curtis Non-Executive Chair
After 8 years in The Royal Air Force, Jon moved to the Imperial Cancer Research Fund where he pioneered the use of ultra high-throughput genomic automation, capable of 46,000 PCRs per hour. In the 1990’s Jon joined GlaxoSmithKline, implementing a high-throughput genomics platform into their drug discovery pipeline. Whilst there he also developed acoustic mixing into compound management, becoming the gold standard across pharma. Jon developed the world’s first commercially viable 1536-well PCR plates, automated thermal & laser plate-sealer, plus automated liquid-handling & tip washing tools to reduce waste and costs. In 2002 Jon co-founded KBioscience with Phil Robinson, utilising ultra high-throughput PCR instrumentation & a suite of automation tools to create the company’s SNPline robotic platform, with a capacity of 250,000 PCRs/day. The business was underpinned by their ground-breaking patented genotyping chemistry, KASP™, which has over 10,000 scientific papers to date. In November 2022 Jon joined 3CR Bioscience acting as an advisor bringing his commercial and scientific experience to the company.