PACEยฎ – Your Universal Solution!
In the rapidly evolving world of genomic research and breeding, having versatile reagents that can seamlessly adapt to different platforms is paramount. Enter PACEยฎ – for platform-agnostic SNP genotyping by the power of allele-specific PCR. This innovative solution is changing the game, offering researchers and breeders a universal toolkit for precision genotyping with unparalleled flexibility and reliability.
Unlocking Genetic Insights with SNP Genotyping and Allele-Specific PCR
SNP genotyping and allele-specific PCR are cornerstones of modern genetic analysis, allowing scientists to track and monitor genetic variations with pinpoint accuracy. With PACE genotyping reagents, you can reach new heights of efficient and accuracy at market-leading prices.
Precision Across Platforms: PACE Genotyping Master Mixes
PACE genotyping master mixes are platform agnostic for precision PCR genotyping. PACEโs patented genotyping chemistry has been meticulously designed to perform across all PCR genotyping platforms and reaction volumes, providing consistently accurate results. In addition, all our PACE genotyping mixes are supplied with Standard, High, Low, or No ROX normalisation dye options for optimal performance.
Join the PACE Revolution
Join the ranks of researchers and breeders who have found affordable precision, flexibility, and reliability with PACE genotyping reagents. PACE genotyping master mixes are compatible with all major PCR genotyping platforms, including 96-, 384-, and 1536- well PCR plates, and Array Tapeยฎ. PACE generates accurate data regardless of the reaction volume; PACE Genotyping master mixes are also suitable for BiomarkX and BiomarkHD automated, chip-based PCR systems from Standard Biotools (formerly Fluidigm) that use microfluidics technology to process samples at nanoliter-scale volumes.
Spotlight on Microfluidics: Scaling Up with PACE and Biomarkโข X9
By harnessing the power of microfluidics technology, PACE enables high-throughput, scalable SNP and Indel marker development and screening. This makes it an ideal solution for large-scale, cost-effective allele-specific PCR analysis and SNP genotyping using microfluidics platforms such as the Biomark X9 System from Standard Biotools. The Biomark platforms offer automated, high-performance PCR at nanolitre volumes and simultaneous monitoring of markers across numerous samples, drastically reducing both time and cost.
Breeders and researcher alike can develop platform-agnostic SNP marker sets on these and similar high-throughput platforms, utilising PACE genotyping reagents for universal reporting. PACE is compatible with multiple other throughput platforms downstream to ensure future-proof automation, and reproducibility.
Read Our New Application Note
Check out our latest app note in collaboration with Standard Biotools, showcasing the exemplary performance of our PACE chemistry on the Biomark X9 System with compelling use case study and data. We included typical data from a prominent public research institute analysing 96 samples across 96 SNPs, revealing remarkable results of tight clustering and high concordance of SNPs. This representative data underscores the accuracy and reliability of our technology even at nanoliter-scale volumes, affirming its utility in diverse research settings. Explore the full app note to delve deeper into the implications of this technology partnership and discover how our innovate solutions can advance your research endeavours.
Next-generation sequencing (NGS) for SNP discovery followed by PACE SNP marker saturation in quantitative trait loci (QTL) intervals is a great, real-world example of the utility of this combination. Designing PACE genotyping assays against SNP variants, high-throughput screening using the Biomark X9 System, and genotyping recombinants on lower-throughput platforms demonstrates the versatility in research and breeding applications.
Figure 1. Example data of 96 samples over 96 SNPs. Data calling (A) from the heat map (B) shows tight clustering and a high concordance of SNPs in the principal component analysis plot. Actual data from a high-throughput genotyping and sequencing technology service provider for a public research institute using PACE genotyping with the Biomark X9.
Conclusion: PACE โ Redefining Genomic Research and Breeding
In conclusion, PACE genotyping master mixes are a game-changer in the world of genomic research and breeding. PACEโs patented, platform-agnostic design, compatibility with high-throughput systems like the BiomarkX9 System from Standard Biotools, and unparalleled performance make it the go-to solution for researchers and breeders looking to unlock the full potential of their genotyping assays.
