3CR BIOSCIENCE NEWS & EVENTS

Welcome to the 3CR Bioscience News and Events page, your go-to source for the latest bioscience news and information from 3CR Bioscience and our wider genotyping community. Stay connected with valuable insights, articles, and announcements.
Poultry_Genetics
News

Exciting New Research in Poultry Genetics

A recent study from the Animal Molecular Genetics Team at Chungnum National University uncovers key genetic factors linked to the carnosine content in Red-Brown Korean Native Chickens (KNC-R). Carnosine plays a crucial role in enhancing both the flavor and health benefits of chicken meat, making this discovery highly relevant for the poultry industry.  Key findings: These genetic insights pave the way for marker-assisted selection (MAS) in breeding programs, enabling the production of chickens with superior flavor and quality. This research highlights how genomic technologies can revolutionize livestock breeding, leading to healthier, stronger-flavored poultry meat.  Read more in our latest article!

News

3CR Bio to Exhibit at Euroseeds Congress 2024 in Copenhagen

We are excited to announce that 3CR Bioscience will be exhibiting at the Euroseeds Congress 2024, taking place in Copenhagen, Denmark, from Sunday, 13 October to Wednesday, 16 October 2024. Visit us at Trade Table 36 in the main exhibitor hall to learn more about our genomic tools for modern plant breeding and explore how our end-to-end solutions can support your research and breeding programs. A key event for the European and international seed sector, the Euroseeds Congress brings together leading companies, researchers, and breeders to exchange knowledge and showcase advancements in plant breeding, crop resilience, quality improvement, and data-driven decision-making. We are looking forward to learning from top-level speakers addressing current and future challenges within the industry and to joining the event’s unique environment to foster valuable connections and invigorate collaboration. Copenhagen is known for its leadership in agricultural innovation and provides the perfect backdrop for this year’s Congress. 3CR Bio is thrilled to be part of this prestigious event and we are looking forward to engaging with industry professionals from around the world. Attending Euroseeds 2024? We would be delighted to meet you! Please get in touch with sarah.holme@3crbio.com to arrange a time. We look forward to seeing you at Euroseeds 2024!

PACE PCR Genotyping Trial Kits
News

INTRODUCING 3CR BIOSCIENCE’S NEW
PACE PCR GENOTYPING TRIAL KITS

Exciting news! 3CR Bioscience proudly unveils its latest offering – our range of PACE PCR Genotyping Trial Kits. These kits of designed for anyone who wants to try PACE genotyping reagents in their lab for the first time, offering a set of validated DNA samples, SNP assays, and PACE Master Mix. This comprehensive kit is meticulously crafted to provide researchers with all the necessary tools for a seamless trial experience, allowing you to experience a new era of genotyping precision. THE SCIENCE BEHIND PACE® GENOTYPING The PACE allele-specific PCR mechanism is a robust methodology utilised for the detection of Single Nucleotide Polymorphisms (SNPs), Insertions and Deletions (Indels), and other sequence variants. For detailed insights into the PACE genotyping chemistry visit our PACE product homepage or read our tech note on SNP and Indel genotyping with PACE. WHAT’S INSIDE THE PACE GENOTYPING TRIAL KITS?    The PACE Genotyping Trial Kits contain everything you need to run a trial PACE® allele-specific PCR Genotyping Reaction on your existing lab equipment.  Available for PACE Genotyping Master Mix, PACE 2.0 Genotyping Master Mix, PACE Multiplex Master Mix, and PACE Nano Genotyping Master Mix. Inside the kit, you’ll find: WHO IS THIS TRIAL KIT FOR? This trial kit is tailored for researchers seeking to explore the capabilities of PACE genotyping reagents in their laboratories. Whether you’re a seasoned scientist looking to adopt a new genotyping method or a novice researcher venturing into the realm of genomics, the PACE PCR Genotyping Trial Kit offers an ideal starting point. TRIAL KIT OVERVIEW Running a trial PACE Genotyping Reaction using the kit is a straightforward process: GEAR UP FOR YOUR GENOTYPING TRIAL To facilitate successful experimentation with the PACE PCR Genotyping Trial Kit, ensure the availability of the following components: START YOUR GENOTYPING JOURNEY HERE With the introduction of the PACE PCR Genotyping Trial Kit, 3CR Bioscience continues its legacy of innovation and commitment to advancing genotyping technologies. Experience the next generation of PCR genotyping with confidence and precision. Embrace the future of genomics with the PACE PCR Genotyping Trial Kit – your gateway to unparalleled genotyping excellence. Order a free PACE Genotyping Trial Kit now

SNP genotyping and GBTS data without the hassle - 3CR Bio lab services
News

SNP genotyping data without the hassle –
3CR Bio lab services now available

3CR Bioscience’s state-of-the-art laboratory services are now online and available to customers in partnership with MolBreeding Biotech and HC Scientific. This exciting collaboration capitalises on the strengths of each partner and allows researchers and breeders access to this unique, high-calibre service partnership for the first time. Driving modern genomics forward The facility is based at 3CR Bioscience’s European facilities North of London and provides a comprehensive range of genotyping services, including DNA extraction, endpoint PCR genotyping, and Genotyping by Target Sequencing (GBTS), to genomic researchers and plant and animal breeders from industry, academia, government, and non-government organisations. See our Genotyping in Action Our Full Lab Service Range: DNA Extraction: Efficient, high-quality nucleic acid extraction service and quality testing. Send us your samples, we’ll do the rest. Endpoint PCR Genotyping: Fluorescent endpoint SNP genotyping as well as Indels and more by PCR, with 3CR Bio’s patented PACE® genotyping reagents. PACE® is the latest in allele-specific PCR technology. It provides consistent performance making it ideal for high-throughput genotyping applications. With our many decades of experience, let us generate top line genotyping data for you. Genotyping By Target Sequencing: Access MolBreeding Biotech’s proprietary Genotyping by Target Sequencing (GBTS) technology and experienced service provision. Genotyping Genies – A sneak peek at the 3CR Bioscience Lab Service Workflow Our Lab Service workflow ensures a hassle-free experience from sample submission to data retrieval. Precision, traceability, and efficiency is built into at every step. Choose from: DNA Extraction only DNA Extraction and PACE® Endpoint Genotyping DNA Extraction and Genotyping by Target Sequencing PACE Endpoint Genotyping Only Genotyping by Target Sequencing only Quick Quote Get started with a fast and easy quote for your project. Simply provide a few project details, and our team will generate a tailored quote within 24 hours so you can make an informed decision. Access Online Portal & Register New Account Create an account on our secure online portal. Registration is quick and straightforward, giving you instant access to our suite of services. Submit a new project request, track existing projects and review completed assignments from your secure account. Samples Arrive at 3CR Bioscience Once your samples arrive at our state-of-the-art facility, they are meticulously logged into our system, and you receive receipt confirmation. Ship Samples to 3CR with Submission Form Package and send your samples to our lab, along with the provided submission form. Your samples’ journey to our facility and precision analysis begins here. Complete Sample Submission Information Fill out sample submission details with ease. Our user-friendly interface makes it simple to provide the required information to get your project started. Samples Processed Our experienced team process your samples for the selected services with expert care, ensuring accurate, reliable results. Email Notification When Results Are Ready Stay informed throughout your project and receive an email notification as soon as your results are available, ready for you to review. Login to Portal to Review and Download Data Files Log in to your portal account to access and review your results. Download data files easily for further analysis.    Visit our Lab Services Web Page “We are genuinely excited about the partnership and new venture of the three companies. By combining our patented PACE® genotyping chemistry for allele-specific PCR and background in global lab services provision, leveraging HC Scientific’s extensive automation systems, and MolBreeding Biotech’s established Genotyping by Targeted Sequencing services, the collaboration is uniquely positioned to disrupt the cost of extraction and genotyping service provision across Europe while ensuring unparalleled data accuracy and customer service. The new partnership offers customers a new choice for a lab services provider with a fresh, well-grounded approach that aims to shake up the market.” Steve Asquith, Managing Director 3CR Bioscience. View the full press release

Plant and Animal Genomics Conference PAG
Animal genomics

Join us at the Plant and Animal Genomic Conference / PAG 31

Join us at The 31st Plant and Animal Genome Conference, January 12th – 17th, in San Diego, CA, USA. We look forward to talking to anyone attending. Find us at Booth 419 in the Exhibit Hall. In addition to 3CR Bioscience’s PACE® technology for SNP genotyping, we will be showcasing our new lab services and high-throughput genotyping instrument range in collaboration with MolBreeding and HC Scientific. Beyond individual products and expertise, our collective aim is to provide highly competitive lab services in both Europe and North America. Together, we represent a fusion of specialised knowledge and resources delivering innovative, affordable, top-tier genotyping solutions. Visit conference website Don’t miss our Industry Workshop: This year, 3CR Bioscience is hosting an exciting line-up of talks in a session titled ‘Accelerating Crop and Animal Breeding Enhancement through High-throughput Genotyping: Harnessing the Power of Genomic Selection’ with MolBreeding Biotech and HC Scientific. Join us for a packed schedule of expert speakers from industry and academia. Date: Monday January 15th Time: 4:00 PM – 6:10 PMLocation: Conference Room ‘Town and Country B’ See our presentation times Find more about 3CR’s genotyping technology in action here.

Assay Designs for SNP genotyping and Indel genotyping
News

Unlocking Top Assay Designs for SNP and Indel Genotyping

Explore our New Tech Note! Discover the secrets of successful genotyping with our Tech Note ‘Top 5 Assay Designs for SNP Genotyping and Indel Genotyping’. This comprehensive guide takes you through the most common assay designs, offering insights into optimal primer positioning, common pitfalls to avoid, and more. Tech Note on SNP Genotyping and Indel Genotyping – contents: A brief introduction to the basics of Allele-Specific PCR and 3CR Bio’s patented PACE® genotyping chemistry Expert technical information and guidance on turning identified SNPs and Indels into user-friendly marker assays. Detailed primer designs for standard biallelic SNPs, single-base and small Indels, as well as large Indels with known or unknown junctions. Practical considerations and recommendations for optimising assay location along your target sequence Tips for successful assay primer sequence selection Answers to frequently asked questions about 3CR Bio’s assay design. Info on 3CR Bio’s free PACE® assay design service and validation options Next level assay applications – PACE® genotyping assays for pathogen and transgenic sequence detection. Download our Technical Note and boost your genotyping success today!

PACE used for SNP genotyping in field crop development
Field Crop Development

New case study with the Field Crop Development Centre, Alberta, Canada

PACE® genotyping by 3CR Bioscience used in Canada! Our latest case study showcases work from the Field Crop Development Centre at Olds College of Agriculture and Technology (FCDC), Alberta, Canada. The biotechnology laboratory at FCDC has been using 3CR Bio’s patented PACE® genotyping to apply modern molecular techniques at their facility and develop enhanced varieties of Barley and Triticale. Read here

Animal genomic research
Animal genomics

Spotlight on animal genomic research for ISAG 2023!

To coincide with the International Society for Animal Genetics Conference in South Africa, 2nd July – 7th July 2023, 3CR Bioscience are highlighting how our patented PACE PCR genotyping technology can accelerate animal genomic research and breeding programs in a new flyer being shared at the conference. Not attending? No problem! Check out the flyer here. See how PACE integrates perfectly into genomic research and breed improvement workflows, plus read published user case studies.

3CR Bioscience Making Science Affordable
News

Now available in our 3CR Bioscience consumbales range: Heat sealing film for PCR plates

We are thrilled to announce the latest addition to our consumables range at 3CR Bioscience: heat sealing film for 96- and 384-well PCR plates. This rigorously tested, permanent seal film complements our rigid frame 384-well PCR plates perfectly. Its superior clarity allows for easy sample visualisation and monitoring, ensuring excellent data quality. Crafted from high-quality materials, the seal offers excellent chemical resistance and plate compatibility. Designed with durability, the film provides a secure seal with precise fit and strong adhesion, safeguarding sample integrity throughout amplification, recycling, and reading. Both seals and our 384-well PCR plates are ideal for automated, high-throughput PCR environments, including robotic handling. The film remains stable during thermal cycling in PCR machines and hydrocyclers, offering performance and convenience across various PCR workflows. With this new addition, we reaffirm our commitment to delivering reliable, high-performance, and affordable products that empower scientists worldwide. Contact us today to include a free sample of PCR plates and seal in your next shipment!

ISAG 2023
News

Exciting expansion work begins on-site at 3CR Bioscience

Work has officially begun on our expansion project here at 3CR Bioscience in Harlow. We are doubling the footprint of our business on-site so we can increase our manufacturing capacity to meet the growing demand for our technology-leading genotyping reagents. This expansion also paves the way for exciting additional products, services, and our growing team. Join us on our journey of innovation and breakthroughs. Together we are shaping the future of genomics! 

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Contact us

MEET OUR TEAM

Steve Asquith Managing Director
Steve began his career in the Genetics Division of GlaxoSmithKline, as part of the team establishing GSK’s high-throughput core genotyping laboratory. Steve joined KBioscience when it was first founded in 2002 and was a key driver in taking the company from a small start-up to a multi-national service laboratory, quickly growing the company’s revenue to over $7.5M p.a. Following the acquisition of Kbioscience by LGC in 2011, Steve was appointed Global Director of Operations for LGC Genomics, responsible for over 100 staff in Europe and N. America, successfully elevating the genotyping products and service business. Steve held a crucial leadership role until he left in 2016. In 2017 Steve joined forces with John Holme to create 3CR Bioscience, a new company with a mission to deliver outstanding, customer-focused genotyping products with innovation and affordability at its core.
Dr. John Holme Technical Director
John joined KBioscience shortly after it was founded, in 2003, and became Head of Technical Development, building the company’s genotyping and DNA extraction product portfolio and service delivery until 2011 when it was acquired by LGC. Post-acquisition, John was appointed Head of Technical Group for LGC Genomics, in charge of all Research & Development and Technical Support activities for the company. In this role John continued to build on the high-quality products and services provided to the companies growing customer base. During the 19 years John has worked in commercial R&D, he has co-invented numerous highly successful products including PACE®, ProbeSure, KASP™, KlearKall, KlearGene, KlearAmp and KlearTaq™, creating breakthrough offerings in genotyping and extraction and generating huge revenues for the companies he has worked in. In 2017, he joined forces with Steve Asquith and started 3CR Bioscience. John is dedicated to developing outstanding, innovative genotyping products and providing the very best technical support to customers globally.
Dr. Nisha JainOperations Director
Nisha has been innovating since the start of her career at Geneform Technologies developing Iso-thermal Genotyping Technologies. Nisha joined KBioscience in 2008, as Senior R&D Scientist and key account Technical Support Scientist, developing KASP and Klearkall performance and coinventing two further versions of KASP. Nisha has more than 15 years’ experience working in molecular biology and genotyping technologies, with extensive experience in the areas of R&D, Quality Assurance and Customer Technical Support. She has technically assisted many giants of the industry with their protocol development and troubleshooting and continues to deliver high-quality support and guidance. In 2018, Nisha joined 3CR Bioscience as Operations Director where she continues to develop PACE and ProbeSure for an increasing range of applications, and to grow 3CR Bioscience’s new product pipeline. Nisha is dedicated to developing outstanding, innovative genotyping products and providing the very best technical support to customers globally.
Nazma Saffin General Manager
For 20 years Nazma Saffin has worked and gained extensive expertise within the genotyping sector. Working at Kbioscience and then LGC, she has held operational leadership posts responsible for manufacturing and laboratory services. With experience of ISO 9001 implementation, production scale up and LEAN operations, Nazma has successfully led highly profitable production departments. Joining 3CR Bioscience in 2022, Nazma is committed to delivering operational excellence.
Jon Curtis Non-Executive Chair
After 8 years in The Royal Air Force, Jon moved to the Imperial Cancer Research Fund where he pioneered the use of ultra high-throughput genomic automation, capable of 46,000 PCRs per hour. In the 1990’s Jon joined GlaxoSmithKline, implementing a high-throughput genomics platform into their drug discovery pipeline. Whilst there he also developed acoustic mixing into compound management, becoming the gold standard across pharma. Jon developed the world’s first commercially viable 1536-well PCR plates, automated thermal & laser plate-sealer, plus automated liquid-handling & tip washing tools to reduce waste and costs. In 2002 Jon co-founded KBioscience with Phil Robinson, utilising ultra high-throughput PCR instrumentation & a suite of automation tools to create the company’s SNPline robotic platform, with a capacity of 250,000 PCRs/day. The business was underpinned by their ground-breaking patented genotyping chemistry, KASP™, which has over 10,000 scientific papers to date. In November 2022 Jon joined 3CR Bioscience acting as an advisor bringing his commercial and scientific experience to the company.