A PCR automation system is an integrated laboratory solution that automates the full PCR workflow, from sample preparation and DNA extraction to PCR setup, thermal cycling, and data analysis. By replacing manual steps with automated instruments, PCR automation systems increase throughput, improve reproducibility, and reduce human error in high-volume genotyping laboratories.
3CR Bioscience offers a cutting-edge range of genotyping instruments designed to streamline laboratory automation systems. Our advanced solutions include MagC 9600 and MagC 384 for automated DNA extraction, the GeneArrayer series for precision liquid handling and plate sealing, the GeneCycler high-throughput water bath thermal cycler, and the GeneScanner for high-speed PCR plate fluorescence scanning.
Whether you need a single instrument or a complete PCR automation system for end-to-end workflow automation, 3cr Bioscience delivers flexible solutions that increase efficiency, reduce manual errors, and support high-performance genotyping at any scale.
Meet the Turbo Grinder, a powerful bead-based tissue homogenizer for plants, animals, and microbes. Processing up to 576 samples per run, it delivers fast, uniform grinding for high-quality downstream DNA analysis. With programmable touchscreen control, flexible dry/wet/frozen modes, and low-noise operation, it streamlines sample prep for genotyping and sequencing workflows.
Meet the MagC 9600 and MagC 384, your all-in-one nucleic acid extraction solutions. These advanced instruments are compatible with magnetic bead-based reagent kits and process up to 384 samples in 25–30 minutes from a range of starting material. With pre-loaded programs, touch-screen operation, and contamination control, they deliver high-quality extractions for genotyping, sequencing, and gene analysis. Streamline your workflow with precise, user-friendly automation.
The GeneArrayer automates sample replication, assay dispensing, pipette washing, and plate sealing in one workstation. With precise nanolitre dispensing, it minimizes reagent and plastic use while ensuring high levels of accuracy. This precision makes the GeneArrayer ideal for assay miniaturisation strategies in high-throughput PCR and SNP genotyping workflows. Featuring a 96-tip head, barcode scanner, and rapid 384-well plate dispensing, the GeneArrayer streamlines liquid handling and dispensing workflows. Upgrade to the GeneArrayer Pro for ultra-high-throughput automation.
The GeneCycler is a high-efficiency water bath thermal cycling instrument. Up to 25 low profile 384-well PCR plates or 20 standard 384-well or 1536-well PCR plates can be cycled per run. The GeneCycler’s integrated touchscreen control panel provides a user-friendly interface to easily create protocols and monitor progress during each run. With an improved heating design, the GeneCycler increases throughput while reducing running costs, using up to 80% less energy than standard Peltier PCR blocks.
Featuring 3 individually temperature-controlled water baths, high-efficiency heating, and a robust basket design, the GeneCycler streamlines and enhances your thermal cycling process.
The GeneScanner is a high-throughput fluorescence scanner for rapid, sensitive signal detection. It features automated plate handling, barcode reading, and full-field scanning with read times as low as 5 seconds per filter. Detecting volumes as low as 1 µL, the GeneScanner supports multiple detection channels across the visible spectrum and a range of PCR plates, and is also duplex compatible. Boost efficiency with fast, precise fluorescence analysis.
Unlock the full spectrum of genotyping possibilities with our comprehensive, modular range of instruments. Explore our end-to-end genotyping automation solutions and discover the perfect fit for your laboratory, ensuring efficiency and accuracy at every step.
WORKFLOW SOLUTIONS
Entry level genotyping lab workflow with manual dispensing into PCR plates run on standard Peltier thermal cycling instruments.
Manual pipetting
Multi-channel pipette manual liquid handling plus Peltier PCR block cycling.
High-speed PCR plate fluorescence scanning.
WORKFLOW SOLUTIONS
Balanced solution offering moderate capacity and speed, perfect for mid-sized labs with growing demands.
Single plate automated extraction
Manual pipetting
Multi-channel pipette manual liquid handling
High-throughput water bath thermal cycler.
High-speed PCR plate fluorescence scanning.
WORKFLOW SOLUTIONS
High-efficiency genotyping for larger labs, providing fast and reliable results with significant sample volumes.
4 plate automated extraction
Automated liquid handling,dispensing and plate sealing workstation.
High-throughput water bath thermal cycler.
High-speed PCR plate fluorescence scanning.
WORKFLOW SOLUTIONS
Top-tier solution designed for extensive genotyping projects, ensuring maximum productivity and rapid data generation.
4 plate automated extraction
Fully automated workstation for sample loading, dispensing & plate sealing.
High-throughput water bath thermal cycler.
High-speed PCR plate fluorescence scanning.
The HyperGeno™ is 3CR Bioscience’s most advanced, high-throughput automation system, delivering a fully integrated, end-to-end genotyping workflow from sample preparation to data analysis. Designed for large-scale molecular breeding and genomics laboratories, it enables true walk-away operation with maximum accuracy, scalability, and efficiency.
As genotyping demand grows, many laboratories are moving from manual PCR setup to automated PCR systems. Automation reduces hands-on time, improves reproducibility, and enables higher-throughput SNP genotyping with fewer manual errors. The table below compares key differences between manual PCR workflows and PCR automation systems.
| Feature / Criteria | Manual PCR | PCR Automation System |
|---|---|---|
| PCR setup | Full manual pipetting | Full or semi-automated liquid handling; |
| Throughput | Low to medium | Medium to ultra-high throughput |
| Hands-on time | High | Very low |
| Reproducibility | Variable, operator-dependent | Highly standardised and reproducible |
| Error rate | Higher risk of pipetting errors | Significantly reduced |
| Contamination risk | Higher due to manual handling | Lower due to fewer manual steps |
| Scalability | Limited | Easily scalable and modular |
| Assay miniaturisation | Difficult | Highly compatible |
| Reagent & plastic usage | Higher | Reduced via precision dispensing |
| Labour costs | High | Lower over time |
| Data consistency | Variable | Consistent across runs |
| Best suited for | Small labs, low volume | High-throughput and industrial labs |
PCR automation increases throughput, improves reproducibility, and significantly reduces pipetting errors and contamination risk. Automated systems also lower long-term costs by reducing reagent waste, plastic consumption, and labour requirements, making them ideal for high-volume genotyping laboratories.
Automated PCR systems are best suited for laboratories processing medium to high sample volumes, including genotyping labs, agricultural breeding programs, and life science facilities that require consistent, scalable, and reproducible PCR workflows.
Yes. Modular PCR automation systems allow laboratories to start with a single automated instrument (e.g. liquid handling or extraction) and expand into a fully integrated, end-to-end PCR automation workflow as throughput requirements grow.
Yes. By standardising liquid handling, thermal cycling conditions, and detection parameters, PCR automation reduces variability between runs and operators, delivering more consistent and reliable genotyping data.
PCR automation systems are highly compatible with SNP genotyping workflows, especially when combined with optimized reagents such as PACE® master mixes. Automation supports assay miniaturisation, multiplexing, and high-density plate formats, enabling efficient SNP analysis at scale.
Compared to manual PCR workflows, automation can reduce hands-on time by 60–90%, depending on workflow complexity and sample volume. This allows laboratory staff to focus on data interpretation rather than repetitive pipetting tasks
Yes. Automated PCR systems minimise manual handling steps, reducing exposure to contaminants and improving overall assay reliability, especially in high-throughput environments.
While the initial investment is higher than manual PCR, automation delivers strong ROI for high-throughput labs by reducing labour costs, reagent consumption, repeat experiments, and operational errors over time.
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John joined KBioscience shortly after it was founded, in 2003, and became Head of Technical Development, building the company’s genotyping and DNA extraction product portfolio and service delivery until 2011 when it was acquired by LGC. Post-acquisition, John was appointed Head of Technical Group for LGC Genomics, in charge of all Research & Development and Technical Support activities for the company. In this role John continued to build on the high-quality products and services provided to the companies growing customer base.
During the 19 years John has worked in commercial R&D, he has co-invented numerous highly successful products including PACE®, ProbeSure, KASP™, KlearKall, KlearGene, KlearAmp and KlearTaq™, creating breakthrough offerings in genotyping and extraction and generating huge revenues for the companies he has worked in. In 2017, he joined forces with Steve Asquith and started 3CR Bioscience. John is dedicated to developing outstanding, innovative genotyping products and providing the very best technical support to customers globally.
Nisha has been innovating since the start of her career at Geneform Technologies developing Iso-thermal Genotyping Technologies. Nisha joined KBioscience in 2008, as Senior R&D Scientist and key account Technical Support Scientist, developing KASP and Klearkall performance and coinventing two further versions of KASP.
Nisha has more than 15 years’ experience working in molecular biology and genotyping technologies, with extensive experience in the areas of R&D, Quality Assurance and Customer Technical Support. She has technically assisted many giants of the industry with their protocol development and troubleshooting and continues to deliver high-quality support and guidance. In 2018, Nisha joined 3CR Bioscience as Operations Director where she continues to develop PACE and ProbeSure for an increasing range of applications, and to grow 3CR Bioscience’s new product pipeline. Nisha is dedicated to developing outstanding, innovative genotyping products and providing the very best technical support to customers globally.
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