This advanced water-bath thermal cycler for PCR sets new standards in efficiency, precision, and sustainability for routine and mid-throughput laboratories. Unlike traditional Peltier-based thermal cyclers, it delivers higher throughput, faster ramp rates and uniform temperature control across every run.
By minimising energy consumption and reducing maintenance requirements, it supports both high-performance workflows and sustainable lab practices. Compared to conventional thermal cyclers, it offers increased throughput and reduced running costs, using 80% less energy.
Designed for laboratories requiring dependable, scalable PCR performance, the GeneCycler combines robust engineering, comprehensive support, and lower lifetime operating costs to deliver long-term value for demanding PCR workflows.
This automated high-throughput water-bath PCR thermal cycler is engineered for large-scale PCR laboratories requiring maximum capacity and efficiency. Designed for ultra-high-throughput workflows, it enables simultaneous processing of up to 40 × 384-well plates per run.
Featuring three independent water baths with integrated circulation, the HyperCycler delivers precise, uniform temperature control across every plate while supporting two-step, three-step, and Touchdown PCR protocols. Its flexible basket system allows laboratories to scale plate numbers according to demand.
Using advanced water-based heat transfer technology, the HyperCycler eliminates conventional ramp delays during cycling, significantly reducing reaction times while achieving exceptional energy efficiency compared to traditional metal block systems.
Built for sustained high-volume operation, it combines industrial-scale throughput, reproducibility, and long-term operational efficiency for demanding PCR environments.
GeneCycler runs up to 20 low-profile 384-well plates or 16 standard 384/1536-well plates per run. HyperCycler processes up to 40 × 384-well plates in a single run for ultra-high-throughput PCR labs.
Advanced water-based heat transfer technology reduces energy consumption by up to 90% compared to Peltier PCR blocks. Even at full capacity, the HyperCycler maintains high efficiency, lowering operational costs and environmental impact.
Three independent circulating water baths ensure uniform temperature distribution and reliable PCR results across large plate volumes.
Automated tank filling, emptying, and scheduled pre-heating or shutdown simplify daily operation while improving reliability and laboratory workflow efficiency.
A zero-maintenance basket system with no moving parts ensures durability and reliability. The intuitive touchscreen interface allows quick setup and easy operation.
Both instruments are compatible with high-precision PCR microplates, enabling rapid, uniform heat transfer and precise temperature control for a wide range of high-throughput PCR applications.
The GeneCycler is a next-generation PCR thermal cycler engineered to maximize throughput, precision, and sustainability. Designed for demanding workflows, it can cycle up to 25 low-profile 384-well PCR plates or 20 standard 384-well or 1536-well plates in a single run, making it ideal for high-throughput molecular applications. Its support for 384- and 1536-well plate formats makes the GeneCycler well suited for assay miniaturisation strategies that reduce reaction volumes while increasing data output. Three individually temperature-controlled water baths (40 °C–98 °C) with ±0.1 °C accuracy ensure highly reliable and reproducible PCR thermal cycling results.
An intuitive touchscreen interface simplifies protocol creation, editing, and real-time monitoring, while the system’s preheating function and flexible cycling modes, including standard and touchdown PCR support diverse research needs. Compared to conventional Peltier-based instruments, the GeneCycler reduces energy consumption by up to 80%, cutting operational costs while promoting sustainable lab practices. By combining advanced thermal control, exceptional capacity, and user-friendly design, this thermal cycler for PCR delivers unmatched efficiency and value.
Our instruments are built for peak performance, durability and exceptional reliability. To ensure they continue operating at their best, we offer a range of support services – available whenever you need them.
Maximise performance with tailored training and a Spares & Support Kit, designed to keep your instrument running smoothly. With first-line remote engineer access and essential spare parts, you can perform routine maintenance as required. Plus, benefit from cost savings with an exclusive discount on your Annual Contract.
For advanced assistance, our expert engineers provide on-site support to keep your instrument performing at its best. With industry-leading service and rapid response times, we help you maintain efficiency and reliability when it matters most.
Low-volume, slim-profile PCR plates offering excellent thermal uniformity and precision for high-throughput PCR workflows.
Rigid, fully-skirted 384-well PCR plate ensuring excellent stability and uniform heating through every thermal cycle.
Secure, airtight PCR sealing film prevents evaporation and contamination during thermal cycling for reliable results.
Unlike traditional Peltier-based PCR thermal cyclers, which typically process one plate per run, the GeneCycler can cycle up to 20–25 plates at once, significantly increasing throughput. It also offers quicker cycling times, more accurate temperature management, and consumes up to 80% less energy, reducing operational costs.
The GeneCycler supports a variety of PCR plate formats, including:
• Low-profile 384-well PCR plates (up to 25 per run).
• Standard 384-well and 1536-well PCR plates (up to 20 per run).
The instrument supports both standard PCR and touchdown PCR, offering flexibility for different experimental needs. It also features a preheating function for optimized start-up efficiency.
With its improved heating design, the GeneCycler consumes up to 80% less energy than standard Peltier block PCR systems. This not only lowers energy costs but also enhances sustainability without compromising performance.
The system features three independently controlled water baths with a temperature range of 40°C–98°C and an accuracy of ±0.1°C, ensuring highly reproducible results across all wells.
Unlock the full spectrum of genotyping possibilities with our comprehensive, modular range of instruments. Explore our end-to-end genotyping solutions and discover the perfect fit for your laboratory, ensuring efficiency and accuracy at every step.
WORKFLOW SOLUTIONS
Entry level genotyping lab workflow with manual dispensing into PCR plates run on standard Peltier thermal cycling instruments.
Manual pipetting
Multi-channel pipette manual liquid handling plus Peltier PCR block cycling.
High-speed PCR plate fluorescence scanning.
WORKFLOW SOLUTIONS
Balanced solution offering moderate capacity and speed, perfect for mid-sized labs with growing demands.
Single plate automated extraction
Manual pipetting
Multi-channel pipette manual liquid handling
High-throughput water bath thermal cycler.
High-speed PCR plate fluorescence scanning.
WORKFLOW SOLUTIONS
High-efficiency genotyping for larger labs, providing fast and reliable results with significant sample volumes.
4 plate automated extraction
Automated liquid handling,dispensing and plate sealing workstation.
High-throughput water bath thermal cycler.
High-speed PCR plate fluorescence scanning.
WORKFLOW SOLUTIONS
Top-tier solution designed for extensive genotyping projects, ensuring maximum productivity and rapid data generation.
4 plate automated extraction
Fully automated workstation for sample loading, dispensing & plate sealing.
High-throughput water bath thermal cycler.
High-speed PCR plate fluorescence scanning.
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John joined KBioscience shortly after it was founded, in 2003, and became Head of Technical Development, building the company’s genotyping and DNA extraction product portfolio and service delivery until 2011 when it was acquired by LGC. Post-acquisition, John was appointed Head of Technical Group for LGC Genomics, in charge of all Research & Development and Technical Support activities for the company. In this role John continued to build on the high-quality products and services provided to the companies growing customer base.
During the 19 years John has worked in commercial R&D, he has co-invented numerous highly successful products including PACE®, ProbeSure, KASP™, KlearKall, KlearGene, KlearAmp and KlearTaq™, creating breakthrough offerings in genotyping and extraction and generating huge revenues for the companies he has worked in. In 2017, he joined forces with Steve Asquith and started 3CR Bioscience. John is dedicated to developing outstanding, innovative genotyping products and providing the very best technical support to customers globally.
Nisha has been innovating since the start of her career at Geneform Technologies developing Iso-thermal Genotyping Technologies. Nisha joined KBioscience in 2008, as Senior R&D Scientist and key account Technical Support Scientist, developing KASP and Klearkall performance and coinventing two further versions of KASP.
Nisha has more than 15 years’ experience working in molecular biology and genotyping technologies, with extensive experience in the areas of R&D, Quality Assurance and Customer Technical Support. She has technically assisted many giants of the industry with their protocol development and troubleshooting and continues to deliver high-quality support and guidance. In 2018, Nisha joined 3CR Bioscience as Operations Director where she continues to develop PACE and ProbeSure for an increasing range of applications, and to grow 3CR Bioscience’s new product pipeline. Nisha is dedicated to developing outstanding, innovative genotyping products and providing the very best technical support to customers globally.
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