Automated nucleic acid extraction

96-well plate DNA extraction instruments for streamlined high-quality automated nucleic extraction from diverse samples in minutes.

H9600 AND H384 DNA EXTRACTION INSTRUMENTS

Single plate (H9600) and 4 plate (H384) DNA extraction instruments suitable for automated magnetic bead-based extractions. Process up to 384 samples in just 25-30 minutes, for purified DNA preps perfect for genotyping, library sequencing, gene chip analysis and more. Use as standalone instruments or incorporate into automated genotyping workflows with other instruments.

Key Features

Fast & Efficient Processing

Capable of extracting nucleic acids from up to 384 samples in just 25-30 minutes.

Superior Extraction Quality

High nucleic acid purity and integrity for downstream applications including PCR, next-generation sequencing, and arrays.

Advanced Contamination Control

Built-in UV lamp and HEPA filter with an independent airflow channel prevent cross-contamination and protect sample integrity.

User-Friendly Interface

Features a touchscreen control panel with pre-loaded extraction programs, allowing for quick and easy operation.

Plug-And-Play Setup

No air or water hook-ups required, allowing for immediate and hassle-free installation in any lab setting.

Compact & Scalable Design

The stackable footprint allows up to three units to be safely stacked, optimizing lab space.

Cost-Effective Operation

Requires only tip combs and plates, reducing plasticware costs for an economical high-throughput solution.

Product Video

H9600 Single plate DNA Extraction instrument

The H9600 is an advanced automated nucleic acid extraction system designed for high-efficiency DNA purification from diverse biological samples, including tissues, blood, bacteria, and fungi. With pre-loaded intelligent extraction programs and magnetic bead-based technology, it ensures superior purity and integrity for downstream applications like PCR, genotyping, and sequencing. Capable of processing up to 96 samples in just 25-30 minutes, the H9600 maximizes laboratory throughput while minimizing manual errors. Its user-friendly touchscreen interface, built-in contamination control, and robust sample protection make it a reliable, cost-effective solution for modern laboratories. The versatile platform supports multiple extraction protocols, offering flexibility for a wide range of research and diagnostic needs.

H9600 full machine view
H384 interior view 2

H384 Four plate DNA extraction instrument

The H384 is a high-throughput automated nucleic acid extraction system designed for labs requiring scalable DNA purification from diverse biological samples, including tissues, blood, bacteria, and fungi. With the capacity to process up to 384 samples (4 x 96-well plates) in just 25-30 minutes, it significantly enhances efficiency while maintaining exceptional purity and integrity. Its pre-loaded protocols, magnetic bead-based purification, and liquid-free transfer system ensure seamless, contamination-free operation. Featuring a user-friendly touchscreen interface, stackable compact design, and low consumable costs, the H384 provides a cost-effective, plug-and-play solution for high-demand genomic applications such as sequencing, genotyping, and gene chip analysis.

PRODUCT SUPPORT

Our instruments are built for peak performance, durability and exceptional reliability. To ensure they continue operating at their best, we offer a range of support services – available whenever you need them.

SPARES & SUPPORT KIT

Maximise performance with tailored training and a Spares & Support Kit, designed to keep your instrument running smoothly. With first-line remote engineer access and essential spare parts, you can perform routine maintenance as required. Plus, benefit from cost savings with an exclusive discount on your Annual Contract.

ON-SITE ENGINEER SUPPORT

For advanced assistance, our expert engineers provide on-site support to keep your instrument performing at its best. With industry-leading service and rapid response times, we help you maintain efficiency and reliability when it matters most.

CONSUMABLES FOR THIS PRODUCT

Extraction Mag Comb

Disposable polypropylene tip combs for use with our H9600 and H384 DNA extraction instruments.

Extraction robot 2.2mL 96 Deep-Well Plates

2.2mL 96 Deep-Well Plates offer exceptional performance in DNA purification and isolation workflows.

FAQ:

Does the H384 support different extraction kits?

Yes! The H9600 and H384 instruments are compatible with a variety of magnetic bead-based nucleic acid extraction kits, providing flexibility for different protocols.

How fast is the H9600 and H384 automated nucleic acid extraction?

The H9600 can process up to 96 samples per run, H384 can process up to 384 samples per run, both completing the extraction process in just 25-30 minutes.

Can the instrument handle different sample types?

Yes, both DNA extraction instruments are compatible with a wide range of biological samples, including leaf, seed, animal tissues, blood, fungi, bacteria, and cultured cells.

What downstream applications are the H9600 and H384 suitable for?

These DNA extraction instruments are ideal for applications such as genotyping, next-gen library sequencing, PCR, gene chip analysis, and other downstream molecular biology processes.

What is the working volume range of the instruments?

The DNA extraction instruments have a working volume range of 20 µL – 1000 µL

Do the instruments allow for customizable extraction protocols?

Yes, the system supports editable extraction programs and has 6 working plate positions, making it highly versatile for different workflows.

How does the H384 compare to other DNA extraction instruments?

Unlike smaller-scale instruments, the H384 provides flexible high-throughput processing (1, 2, 3, or 4 plates per run), completing extractions in just 25-30 minutes while maintaining superior extraction quality.

How many samples can the H384 process at once?

The H384 can process up to 384 samples per run by handling four 96-well plates simultaneously, significantly increasing throughput.

Are the H9600 and H384 easy to set up?

Yes! The plug-and-play design means the instruments do not require air or water hook-ups, making them simple to install and operate right out of the box.

Can multiple H384 units be used together?

Yes! The compact design allows up to three H384 units to be safely stacked, optimizing space in the lab.

What happens if there is a power failure during a run?

The H9600 and H384 feature power failure protection, allowing the instruments to resume the previous experiment without the need for re-extraction, reducing the risk of sample loss.

How does the H9600 and H384 prevent sample contamination?

The instrument is equipped with a built-in UV lamp and an external HEPA filter with an independent airflow channel, effectively minimizing the risk of cross-contamination.

Does the H9600 and H384 require frequent maintenance?

No, the modular and compact design minimizes maintenance requirements, ensuring consistent and long-lasting performance.

End-to-end genotyping solutions

Unlock the full spectrum of genotyping possibilities with our comprehensive, modular range of instruments. Explore our end-to-end genotyping solutions and discover the perfect fit for your laboratory, ensuring efficiency and accuracy at every step.

LOW

WORKFLOW SOLUTIONS

Entry level genotyping lab workflow with manual dispensing into PCR plates run on standard Peltier thermal cycling instruments.

  • Manual pipetting

    Multi-channel pipette manual liquid handling plus Peltier PCR block cycling.

  • GeneScanner:

    High-speed PCR plate fluorescence scanning.

Medium

WORKFLOW SOLUTIONS

Balanced solution offering moderate capacity and speed, perfect for mid-sized labs with growing demands.

  • H9600:

    Single plate automated extraction

  • Manual pipetting

    Multi-channel pipette manual liquid handling

  • GeneCycler:

    High-throughput water bath thermal cycler.

  • GeneScanner:

    High-speed PCR plate fluorescence scanning.

High

WORKFLOW SOLUTIONS

High-efficiency genotyping for larger labs, providing fast and reliable results with significant sample volumes.

Ultra High

WORKFLOW SOLUTIONS

Top-tier solution designed for extensive genotyping projects, ensuring maximum productivity and rapid data generation.

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MEET OUR TEAM

Steve Asquith Managing Director
Steve began his career in the Genetics Division of GlaxoSmithKline, as part of the team establishing GSK’s high-throughput core genotyping laboratory. Steve joined KBioscience when it was first founded in 2002 and was a key driver in taking the company from a small start-up to a multi-national service laboratory, quickly growing the company’s revenue to over $7.5M p.a. Following the acquisition of Kbioscience by LGC in 2011, Steve was appointed Global Director of Operations for LGC Genomics, responsible for over 100 staff in Europe and N. America, successfully elevating the genotyping products and service business. Steve held a crucial leadership role until he left in 2016. In 2017 Steve joined forces with John Holme to create 3CR Bioscience, a new company with a mission to deliver outstanding, customer-focused genotyping products with innovation and affordability at its core.
Dr. John Holme Technical Director
John joined KBioscience shortly after it was founded, in 2003, and became Head of Technical Development, building the company’s genotyping and DNA extraction product portfolio and service delivery until 2011 when it was acquired by LGC. Post-acquisition, John was appointed Head of Technical Group for LGC Genomics, in charge of all Research & Development and Technical Support activities for the company. In this role John continued to build on the high-quality products and services provided to the companies growing customer base. During the 19 years John has worked in commercial R&D, he has co-invented numerous highly successful products including PACE®, ProbeSure, KASPâ„¢, KlearKall, KlearGene, KlearAmp and KlearTaqâ„¢, creating breakthrough offerings in genotyping and extraction and generating huge revenues for the companies he has worked in. In 2017, he joined forces with Steve Asquith and started 3CR Bioscience. John is dedicated to developing outstanding, innovative genotyping products and providing the very best technical support to customers globally.
Dr. Nisha JainOperations Director
Nisha has been innovating since the start of her career at Geneform Technologies developing Iso-thermal Genotyping Technologies. Nisha joined KBioscience in 2008, as Senior R&D Scientist and key account Technical Support Scientist, developing KASP and Klearkall performance and coinventing two further versions of KASP. Nisha has more than 15 years’ experience working in molecular biology and genotyping technologies, with extensive experience in the areas of R&D, Quality Assurance and Customer Technical Support. She has technically assisted many giants of the industry with their protocol development and troubleshooting and continues to deliver high-quality support and guidance. In 2018, Nisha joined 3CR Bioscience as Operations Director where she continues to develop PACE and ProbeSure for an increasing range of applications, and to grow 3CR Bioscience’s new product pipeline. Nisha is dedicated to developing outstanding, innovative genotyping products and providing the very best technical support to customers globally.
Nazma Saffin General Manager
For 20 years Nazma Saffin has worked and gained extensive expertise within the genotyping sector. Working at Kbioscience and then LGC, she has held operational leadership posts responsible for manufacturing and laboratory services. With experience of ISO 9001 implementation, production scale up and LEAN operations, Nazma has successfully led highly profitable production departments. Joining 3CR Bioscience in 2022, Nazma is committed to delivering operational excellence.
Jon Curtis Non-Executive Chair
After 8 years in The Royal Air Force, Jon moved to the Imperial Cancer Research Fund where he pioneered the use of ultra high-throughput genomic automation, capable of 46,000 PCRs per hour. In the 1990’s Jon joined GlaxoSmithKline, implementing a high-throughput genomics platform into their drug discovery pipeline. Whilst there he also developed acoustic mixing into compound management, becoming the gold standard across pharma. Jon developed the world’s first commercially viable 1536-well PCR plates, automated thermal & laser plate-sealer, plus automated liquid-handling & tip washing tools to reduce waste and costs. In 2002 Jon co-founded KBioscience with Phil Robinson, utilising ultra high-throughput PCR instrumentation & a suite of automation tools to create the company’s SNPline robotic platform, with a capacity of 250,000 PCRs/day. The business was underpinned by their ground-breaking patented genotyping chemistry, KASP™, which has over 10,000 scientific papers to date. In November 2022 Jon joined 3CR Bioscience acting as an advisor bringing his commercial and scientific experience to the company.