1536-Well PCR Plates for Ultra-High-Throughput

1536 well plate designed for ultra-high-throughput PCR applications, featuring a black microplate format for optimal performance, automation compatibility, and consistent low-volume results. 
back to all products
1536 well plate

Detailed Product Description

  • SBS/ANSI-compliant layout
  • Laser Sealer compliant
  • Suitable for reaction volumes from 5 µL to 0.5 µL

Applications and Benefits

  • 3CR Bio End-to-End solutions
  • 3CR Bio’s 20- and 40- plate water bath systems, as well as other water bath PCR systems.

Packaging

  • Supplied in packs of 100 plates
  • Also available in smaller packs of 25

Typical Applications

  • High-throughput PCR
  • Large-scale genotyping
  • Automated screening workflows
  • Ultra-low volume assay development

About

The 3CR Bio 1536-well plate is engineered for ultra-high-throughput PCR and genotyping workflows, enabling reliable amplification at sub-microlitre volumes. This black 1536-well PCR plate supports miniaturised reactions while maintaining consistent performance across large sample sets. 

Manufactured from high-quality polypropylene, the plate reduces reagent consumption and overall assay costs, making it ideal for large-scale screening and high-density genotyping applications. 

With 1536 wells in a standard SBS/ANSI footprint, this plate delivers four times the density of a 384 well plate while maintaining full compatibility with automated liquid handling and thermal cycling systems. Its precise 1536 well plate dimensions ensure seamless integration into existing laboratory workflows. 

 

Key Features & Benefits 

  • 1536 well SBS/ANSI format
    High-density design minimises throughput within a standard microplate footprint. 
  • Optimised for ultra-low volumes (~0.5 µL)
    Enables cost-efficient PCR workflows with minimal reagent usage. 
  • Laser sealing compatible
    Raised well rims ensure secure sealing and consistent results. 
  • Automation-ready design
    Compatible with standard robotic liquid handling systems. 
  • Standardised plate dimensions
    Ensures compatibility with SBS/ANSI-compliant instruments and workflows. 
  • Pre-barcoded for tracking
    Simplifies sample identification in high-throughput environments. 
  • Broad system compatibility
    Works with 3CR Bio water bath systems and other PCR platforms. 

 

Choose 3CR Bioscience 1536-well PCR plates for reliable ultra-high-throughput performance, precise dimensions, and seamless automation integration in demanding laboratory environments. 

Documentation

No related documents found.

FAQ:

Are these plates compatible with automated liquid handling systems?

Yes, the plates are designed for full compatibility with high-throughput automation platforms, including robotic liquid handlers and plate handlers. They meet standard SBS footprint specifications for easy integration.

Can these plates be used with standard PCR instruments?

Only instruments specifically designed for 1536-well formats can be used. Check your thermal cycler’s specifications for compatibility.

Do the plates support uniform thermal cycling?

Yes. The plates are engineered with thin, consistent well walls to ensure:

  • Efficient heat transfer 
  • Uniform temperature distribution 
  • Reliable and reproducible PCR results 

How do I know if 1536-well plates are right for my lab?

If your workflow involves:

  • Processing thousands of samples 
  • High reagent costs 
  • Automated liquid handling 

then upgrading to 1536-well plates can significantly improve efficiency and reduce costs.

How should the plates be stored?

Store plates in a clean, dry environment at room temperature, away from direct sunlight and contamination sources. Keep them sealed in original packaging until use.

What are 1536-well PCR plates used for?

1536-well PCR plates are designed for ultra–high-throughput applications, enabling thousands of PCR reactions in a single plate. They are commonly used in genotyping, screening assays, and large-scale genomic studies.

What are the key benefits of using 1536-well plates over 384-well or 96-well formats?

  • Significantly higher throughput per run 
  • Reduced reagent consumption per reaction 
  • Lower cost per data point 
  • Increased efficiency in automated workflows 

They are ideal for labs scaling up operations or handling large sample numbers.

What reaction volumes are supported?

Typical working volumes range from 0.5 µL to 5 µL, depending on your protocol and instrumentation. Low-volume compatibility helps minimise reagent costs while maintaining performance.

What sealing options are compatible with these plates?

Currently these plates are compatible with laser sealers. Proper sealing ensures minimal evaporation, especially critical for low-volume reactions.

[fibosearch]

Quick Links:

Documentation
PACE User Manual
PACE Certificate

New customer &#8594

← Back to log in
This field is for validation purposes and should be left unchanged.
Name(Required)
Consent(Required)

Contact us

clear
SEND

Resolve Genotyping Challenges. With One Practical Guide.

From failed amplification to scattered cluster plots — this guide provides structured, expert-backed solutions for the 7 most common PACE® genotyping issues.
get more information

"(Required)" indicates required fields

This field is for validation purposes and should be left unchanged.
I’d like to sign up for the newsletter
Consent to privacy policy(Required)

MEET OUR TEAM

Steve AsquithManaging Director
Steve began his career in the Genetics Division of GlaxoSmithKline, as part of the team establishing GSK’s high-throughput core genotyping laboratory. Steve joined KBioscience when it was first founded in 2002 and was a key driver in taking the company from a small start-up to a multi-national service laboratory, quickly growing the company’s revenue to over $7.5M p.a. Following the acquisition of Kbioscience by LGC in 2011, Steve was appointed Global Director of Operations for LGC Genomics, responsible for over 100 staff in Europe and N. America, successfully elevating the genotyping products and service business. Steve held a crucial leadership role until he left in 2016. In 2017 Steve joined forces with John Holme to create 3CR Bioscience, a new company with a mission to deliver outstanding, customer-focused genotyping products with innovation and affordability at its core.
Dr. John HolmeTechnical Director

John joined KBioscience shortly after it was founded, in 2003, and became Head of Technical Development, building the company’s genotyping and DNA extraction product portfolio and service delivery until 2011 when it was acquired by LGC. Post-acquisition, John was appointed Head of Technical Group for LGC Genomics, in charge of all Research & Development and Technical Support activities for the company. In this role John continued to build on the high-quality products and services provided to the companies growing customer base.

During the 19 years John has worked in commercial R&D, he has co-invented numerous highly successful products including PACE®, ProbeSure, KASP™, KlearKall, KlearGene, KlearAmp and KlearTaq™, creating breakthrough offerings in genotyping and extraction and generating huge revenues for the companies he has worked in. In 2017, he joined forces with Steve Asquith and started 3CR Bioscience. John is dedicated to developing outstanding, innovative genotyping products and providing the very best technical support to customers globally.

Dr. Nisha JainOperations Director

Nisha has been innovating since the start of her career at Geneform Technologies developing Iso-thermal Genotyping Technologies. Nisha joined KBioscience in 2008, as Senior R&D Scientist and key account Technical Support Scientist, developing KASP and Klearkall performance and coinventing two further versions of KASP.

Nisha has more than 15 years’ experience working in molecular biology and genotyping technologies, with extensive experience in the areas of R&D, Quality Assurance and Customer Technical Support. She has technically assisted many giants of the industry with their protocol development and troubleshooting and continues to deliver high-quality support and guidance. In 2018, Nisha joined 3CR Bioscience as Operations Director where she continues to develop PACE and ProbeSure for an increasing range of applications, and to grow 3CR Bioscience’s new product pipeline. Nisha is dedicated to developing outstanding, innovative genotyping products and providing the very best technical support to customers globally.

Nazma SaffinGeneral Manager

For 20 years Nazma Saffin has worked and gained extensive expertise within the genotyping sector. Working at Kbioscience and then LGC, she has held operational leadership posts responsible for manufacturing and laboratory services. With experience of ISO 9001 implementation, production scale up and LEAN operations, Nazma has successfully led highly profitable production departments. Joining 3CR Bioscience in 2022, Nazma is committed to delivering operational excellence.

Greig PollandAutomation and Support Manager

Greig is a hands-on automation specialist and team leader with a strong background in laboratory and industrial automation. He has spent over 25 years developing, installing, and supporting automated systems that transformed laboratory workflows. During this time, Greig worked closely with scientists and engineers to tailor automation solutions for genotyping and molecular biology, an experience that sparked his lasting passion for combining technology with practical science.

Since then, Greig has built on that foundation through leadership roles where he leads automation and support operations. He’s known for being approachable, commercially minded, and deeply committed to helping teams and customers get the best from their technology.

Whether managing a complex automation rollout or helping a customer troubleshoot in real time, Greig brings a thoughtful, collaborative approach that keeps people ,not just machines, at the centre of what he does.

Daniel LawsonMarketing Manager
Daniel is a strategically minded marketing and communications professional with over a decade of experience delivering integrated, multi-channel campaigns across healthcare, legal and not-for-profit sectors. He has a strong track record in building brand visibility, driving engagement and supporting revenue growth through audience-focused marketing.
Prior to joining 3CR Bioscience in 2025, Daniel held senior marketing roles where he led strategic communications, managed brand development and delivered high-impact digital and content campaigns. His experience spans SEO, CRM, PR, events and stakeholder engagement, with a particular strength in translating complex messages into clear, compelling content.
At 3CR Bioscience, Daniel is responsible for shaping and executing the company’s marketing strategy, enhancing brand presence and supporting commercial growth through targeted, data-driven campaigns.