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3CR Bioscience’s Cutting-Edge SNP Genotyping Instrumentation: High-Throughput Automation Powered by PACE®

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3CR Bioscience’s Cutting-Edge SNP Genotyping Instrumentation: High-Throughput Automation Powered by PACE®

Our innovative genotyping instrumentation range is revolutionising high-throughput genomics across agriculture and life sciences. Paired with our patented PACE® genotyping reagents, these state-of-the-art tools are enhancing SNP genotyping throughput, efficiency, and precision by providing unparalleled performance, efficiency and value in labs worldwide.

Unlock the Full Potential of SNP Genotyping with Our Comprehensive Instrumentation

Our new range of instruments in partnership with HC Scientific, is tailored for laboratories of all sizes and throughput requirements, ensuring that every lab can benefit from the latest in genotyping automation. Whether you’re working with low, medium, high, or ultra-high throughput workflows, our end-to-end solutions offer the flexibility and scalability to meet your specific needs.

Instrumentation Overview:

HC9600 and HC384

Fully automated nucleic acid extraction systems for high-quality nucleic acid extraction and purification using magnetic bead-based reagents. Ideal for SNP genotyping, library sequencing, gene chip analysis, and more. These fully automated nucleic acid extraction systems deliver rapid, high-quality extractions from a wide range of sample types. With pre-loaded intelligent programs and compatibility with magnetic bead-based reagent kits, they ensure streamlined and reliable results for genotyping, sequencing, and more.

GeneArrayer and GeneArrayer Pro

Automated liquid handling workstations designed for sample replication, low-volume assay dispensing, plate sealing, and more. On-deck sonicating washing reduces tip consumption and costs. These automated liquid handling workstations integrate sample replication, low-volume dispensing, and plate sealing into a single platform. With precise nanolitre dispensing and advanced nozzle cleaning technology, these instruments reduce reagent consumption, minimize error, and optimize lab workflows.

GeneCycler

A high-efficiency water bath thermal cycling instrument. Up to 20 low profile 384-well PCR plates or 16 standard 384-well or 1536-well PCR plates can be cycled each run. The GeneCycler’s integrated touchscreen control panel provides a user-friendly interface to easily create protocols and monitor progress during each run. With an improved heating design, the GeneCycler increases throughput while reducing running costs, using up to 80% less energy than standard Peltier PCR blocks.Featuring 3 individually temperature-controlled water baths, high-efficiency heating, and a robust basket design, the GeneCycler streamlines and enhances your thermal cycling process.

GeneScanner

High-speed plate scanner for accurate fluorescence detection and analysis with excellent sensitivity and resolution. It ensures reliable data across various throughput levels. A high-throughput fluorescence scanning instrument that offers fast, sensitive, and accurate signal detection. With full-field scanning technology and flexible detection channels, the GeneScanner supports miniaturized reaction volumes and provides rapid data analysis across a broad range of PCR plates.

Spotlight on the GeneCycler

This advanced water bath thermal cycler sets new standards in efficiency, precision, and sustainability – outperforming traditional Peltier-based thermal cyclers and leading competitors while offering incredible value, support and cost-benefits.

Why Choose GeneCycler?

🔬 Unmatched Throughput: Run up to 20 low profile 384-well PCR plates per run or 16 standard 384- or 1536-well plates.

🌟 Energy Efficient: Uses up to 90% less energy than standard Peltier PCR blocks, reducing costs and environmental impact.

💧 Smart Water Management: Auto-filling and emptying of water tanks with scheduled pre-heating and shutdown.

🛠 Robust Design: Zero-maintenance basket design with no moving parts for enhanced reliability.

🖥 User-Friendly: Intuitive touchscreen interface for easy setup and operation.

💬 Outstanding Support: Our top-tier engineering and customer support ensure your success.

Don’t settle for less when you can have the best. Experience the superior engineering and performance of the GeneCycler and take your PCR genotyping to new heights! Watch our video to see the GeneCycler in action!

Tailored Workflow Solutions for Every Laboratory

Our modular genotyping solutions are designed to fit seamlessly into your laboratory, regardless of your throughput needs. Here’s how our instruments can streamline your workflow:


⏵Low Throughput Example Workflow:

Entry level genotyping lab workflow with manual dispensing into PCR plates run on standard Peltier thermal cycling instruments.

  • Manual liquid handling paired with Peltier thermal cycling
  • High-speed fluorescence scanning using the GeneScanner

⏵⏵Medium Throughput Example Workflow:

A balanced solution offering moderate capacity and speed, perfect for mid-sized labs with growing demands.

  • Single-plate automated extraction (HC9600)
  • Manual liquid handling
  • High-throughput thermal cycling with the GeneCycler
  • High-speed fluorescence scanning with the GeneScanner.

⏵⏵⏵High Throughput Example Workflow:

High-efficiency genotyping for larger labs, providing fast and reliable results with significant sample volumes.

  • 4-plate automated extraction with the HC384
  • Liquid handling with the GeneArrayer
  • High-throughput thermal cycling with the GeneCycler
  • High-throughput fluorescence scanning with the GeneScanner

⏵⏵⏵⏵Ultra-High Throughput Example Workflow:

Top-tier solution designed for extensive genotyping projects, ensuring maximum productivity and rapid data generation.

  • 4-plate automated extraction with the HC384
  • Complete liquid handling and dispensing automation the GeneArrayer Pro
  • High-throughput thermal cycling with the GeneCycler
  • High-throughput fluorescence scanning with the GeneScanner

Elevate Your Genotyping with 3CR Bio

3CR Bio’s new range of genotyping instrumentation, powered by our PACE® technology, delivers comprehensive solutions for labs aiming to achieve the highest levels of accuracy and efficiency. Whether you’re processing hundreds or thousands of samples, our tools are designed to scale with your needs, ensuring reliable results every time.

Explore the possibilities of our instrumentation range and discover how we can help your lab achieve its genotyping goals. Contact us today to learn more about our products and how they can enhance your research and breeding programs.

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Our product portfolio for your PCR genotyping workflow

Our portfolio of products and services include PACE® genotyping chemistry, instruments, and lab services to streamline every step of your workflow. Designed for life sciences, biotech, and agricultural research, our high-performance reagents, reliable instruments, and expert lab support help you achieve accurate, consistent results while reducing time and costs – making science affordable.

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MEET OUR TEAM

Steve AsquithManaging Director
Steve began his career in the Genetics Division of GlaxoSmithKline, as part of the team establishing GSK’s high-throughput core genotyping laboratory. Steve joined KBioscience when it was first founded in 2002 and was a key driver in taking the company from a small start-up to a multi-national service laboratory, quickly growing the company’s revenue to over $7.5M p.a. Following the acquisition of Kbioscience by LGC in 2011, Steve was appointed Global Director of Operations for LGC Genomics, responsible for over 100 staff in Europe and N. America, successfully elevating the genotyping products and service business. Steve held a crucial leadership role until he left in 2016. In 2017 Steve joined forces with John Holme to create 3CR Bioscience, a new company with a mission to deliver outstanding, customer-focused genotyping products with innovation and affordability at its core.
Dr. John HolmeTechnical Director

John joined KBioscience shortly after it was founded, in 2003, and became Head of Technical Development, building the company’s genotyping and DNA extraction product portfolio and service delivery until 2011 when it was acquired by LGC. Post-acquisition, John was appointed Head of Technical Group for LGC Genomics, in charge of all Research & Development and Technical Support activities for the company. In this role John continued to build on the high-quality products and services provided to the companies growing customer base.

During the 19 years John has worked in commercial R&D, he has co-invented numerous highly successful products including PACE®, ProbeSure, KASP™, KlearKall, KlearGene, KlearAmp and KlearTaq™, creating breakthrough offerings in genotyping and extraction and generating huge revenues for the companies he has worked in. In 2017, he joined forces with Steve Asquith and started 3CR Bioscience. John is dedicated to developing outstanding, innovative genotyping products and providing the very best technical support to customers globally.

Dr. Nisha JainOperations Director

Nisha has been innovating since the start of her career at Geneform Technologies developing Iso-thermal Genotyping Technologies. Nisha joined KBioscience in 2008, as Senior R&D Scientist and key account Technical Support Scientist, developing KASP and Klearkall performance and coinventing two further versions of KASP.

Nisha has more than 15 years’ experience working in molecular biology and genotyping technologies, with extensive experience in the areas of R&D, Quality Assurance and Customer Technical Support. She has technically assisted many giants of the industry with their protocol development and troubleshooting and continues to deliver high-quality support and guidance. In 2018, Nisha joined 3CR Bioscience as Operations Director where she continues to develop PACE and ProbeSure for an increasing range of applications, and to grow 3CR Bioscience’s new product pipeline. Nisha is dedicated to developing outstanding, innovative genotyping products and providing the very best technical support to customers globally.

Nazma SaffinGeneral Manager
For 20 years Nazma Saffin has worked and gained extensive expertise within the genotyping sector. Working at Kbioscience and then LGC, she has held operational leadership posts responsible for manufacturing and laboratory services. With experience of ISO 9001 implementation, production scale up and LEAN operations, Nazma has successfully led highly profitable production departments. Joining 3CR Bioscience in 2022, Nazma is committed to delivering operational excellence.
Greig PollandAutomation and Support Manager

Greig is a hands-on automation specialist and team leader with a strong background in laboratory and industrial automation. He has spent over 25 years developing, installing, and supporting automated systems that transformed laboratory workflows. During this time, Greig worked closely with scientists and engineers to tailor automation solutions for genotyping and molecular biology, an experience that sparked his lasting passion for combining technology with practical science.

Since then, Greig has built on that foundation through leadership roles where he leads automation and support operations. He’s known for being approachable, commercially minded, and deeply committed to helping teams and customers get the best from their technology.

Whether managing a complex automation rollout or helping a customer troubleshoot in real time, Greig brings a thoughtful, collaborative approach that keeps people ,not just machines, at the centre of what he does.